List of Posters
Posters on Main Workshop Day1 (Tuesday May 07, 2024, 2024)
Ligand-Binding PK, Biomarkers and Biotherapeutics Immunogenicity Assays
Day1-P01: "Advancing Pharmacokinetic Profiling: Method Development of DAR-Insensitive Ligand Binding Assay for ADC Drug Detection in Biological Matrix"
Poster Presenter: Xiaonan Liu (Frontage Laboratories, Exton, Pennsylvania, United States)
Co-Authors: Tao Xu, Fengsong Qin, Nan Zhang, John Lin
Frontage Laboratories
Day1-P02: "Quantitation of a Complement Receptor CR2-CR1 Fusion Protein in Ocular and Serum Matrices Using a Dual Electrochemiluminescent Sandwich Immunoassay"
Poster Presenter: Kara Shumansky (Kriya Therapeutics, Durham, North Carolina, United States)
Co-Authors: Kara Shumansky, James Coyne PhD, Rachel Eclov PhD, Uma Karadge PhD, and Angela Ambakhutwala PhD
Kriya Therapeutics
Day1-P03: "Strategies to improve assay sensitivity to quantify therapeutic oligonucleotides"
Poster Presenter: Elizabeth Ruiz Lancheros (Altasciences, Laval, Quebec, Canada)
Co-Authors: Vaibhav Naresh Mehta, Elizabeth Ruiz Lancheros, Danielle Salha
Altasciences
Day1-P04: "Singlicate analysis in ligand binding assays from discovery to regulated clinical studies: Implementation strategies and benefits "
Poster Presenter: Quentin Osseman (Altasciences, Laval, Quebec, Canada)
Co-Authors: Quentin Osseman, Vasken Parsekhian, Danielle Salha
Altasciences
Day1-P05: "Immunogenicity of protein therapeutics in oncology: Influence of testing method and sampling frequency on reported anti-drug antibody incidence rates"
Poster Presenter: James Zanghi (Genentech, Los Altos, California, United States)
Co-Authors: James Zanghi [presenter]1, Maxime Usdin2, Valerie Quarmby1 ,Yuan Song1, Coen Bernaards3, Laura Liao3, Joel Laxamana3, Benjamin Wu4, Steven Swanson1, Patty Siguenza1
1 BioAnalytical Sciences, Genentech
2 gRED Computational Sciences, Genentech
3 PD Data Sciences, Genentech
4 Clinical Pharmacology, Genentech
Day1-P06: "Improvements to Alnuctamab immunogenicity assay to enable support of pivotal studies"
Poster Presenter: Madhan Masilamani (Bristol Myers Squibb, Princeton, New Jersey, United States)
Co-Authors: Patrick Hellander, Pathanjali Kadiyala, Brittany Oxendine, Kristen Trexler, Laura Kelly, Vibha Jawa, Johanna Mora
Bristol Myers Squibb, Lawrenceville, NJ
PPD Bioanalytical Laboratory, Richmond, VA
Day1-P07: "An Anti-Drug Antibody Assay for ADC drug PYX-201 in Human Plasma"
Poster Presenter: Diana Adhikari (Pyxis Oncology, boston, Massachusetts, United States)
Co-Authors: Diana Adhikari; Feng Yin, Ana Lara Rojo; Laura Kelly; Areeg Ibdah; Chengfeng Merriman, Jianwen Feng, Kristen Trexler, Ann Turner Dunford, Roxana Ospina, Mike Dyszel, Shawn Harriman, Frank Wang, Jan Pinkas
Pyxis Oncology Inc., Boston, MA 02118
PPD Laboratory Services, Richmond, VA 23230
Day1-P08: "Domain specific anti-drug antibody or neutralizing antibody assays? Are they both needed to study the clinical immunogenicity of Abatacept?"
Poster Presenter: Kamala Bhavaraju (Dr. Reddy, Hyderabad, Other/None, India)
Co-Authors: Mansi Dhananjaya Jakhade1, Kajal1, Mahesh Kumar 2, Aparna Kasinath2, and Narendra Maharaj1
Dr. Reddy’s Laboratories Ltd. Bachupally, Hyderabad 5000590, Telangana Hyderabad, India [1] and Syngene International Limited III Floor, Tower 1, Semicon Park, Electronics City Phase II Bengaluru 560100, India. [2].
Day1-P09: "Automation of ADA/NAb Enrichment Using PhyTip® technology on the Hamilton Liquid Handling System"
Poster Presenter: Minlei Zhang (Pfizer Inc., Andover, Massachusetts, United States)
Co-Authors: Minlei Zhang, Michael Luong, Ying Wang and Alison Joyce
Pfizer Inc.
Day1-P10: "Anti-Drug Antibody (ADA) Assay for Xpro 1595, a Self-Assembling Trimer: Alternative to Standard Bridging or ACE Approaches"
Poster Presenter: Jing Liu (Q2 Solutions, Indianapolis, Indiana, United States)
Co-Authors: Jing Liu1, Thomas Berg1, Christa Gunawan1, David Smith1, Aundria Liggins1, Richard Snyder1, Raymond J. Tesi, MD2
1Q2 Solutions, 7840 Innovation Blvd Indianapolis, IN 46278; 2. INmune Bio Inc.
Day1-P11: "Three Different Strategies to Mitigate HER2 Target Interference in Anti-drug Antibody (ADA) Assays: Different Solutions under Different Situation"
Poster Presenter: Weihua Gu (Shanghai Xihua Scientific Co., Ltd., Shanghai, Other/None, China)
Co-Authors: Three Different Strategies to Mitigate HER2 Target Interference in Anti-drug Antibody (ADA) Assays: Different Solutions under Different Situation
Shanghai Xihua Scientific Co.,Ltd.
*Corresponding author. Shanghai Xihua Scientific Co.,Ltd., Building 6, Lane 118, Furonghua Road, Pudong New Area, Shanghai, China.
E-mail address: weihua_gu@xihuasci.com.
Day1-P12: "Resolving Target Interference by Viral Antigen in an Immunogenicity ACE Assay "
Poster Presenter: Nicholas Frecker (B2S Life Sciences, Franklin, Indiana, United States)
Co-Authors: Mark O'Dell, Ronald R. Bowsher
B2S Life Sciences
Day1-P13: "Orthogonal approaches in immunogenicity assays to enhance drug tolerance "
Poster Presenter: Thangamma Subramani (Syngene International limited, Bangalore, Other/None, India)
Co-Authors: Thangamma K.S, Sathyaa R, Aparna Kasinath and Mahesh Kumar
Syngene International, Bangalore, India
Day1-P14: "A Screening-Only Generic Method Approach to Nonclinical Anti-Drug Antibody Assessment with Cost and Time Savings, and Support of 4Rs initiatives."
Poster Presenter: Katherine Malone (Charles River Laboratories, Sparks, Nevada, United States)
Co-Authors: Malone, Katherine; Saran, Anand, Ardelean, Rianna and Mouradian, Michael
Charles River Laboratories
Day1-P15: "Step by Step Approach for Highly Drug Tolerant Bridging ADA assays "
Poster Presenter: Brigitte Pellerin (Syneos Health Clinique, QUEBEC, Quebec, Canada)
Co-Authors:
Day1-P16: "Electrochemilumiscence (ECL) Bridging Assays for Detection of Anti-drug Antibodies to Peptide Drug and Cross-reactive Antibodies to Endogenous Peptides"
Poster Presenter: Fangfang Chen (Boehringer Ingelheim, Ridgefield, Connecticut, United States)
Co-Authors: Xiaolong He, Yan Mao and Kelly Coble
Boehringer Ingelheim
Day1-P17: "Evaluation of Design of Experiment (DoE) framework in neutralizing antibody (nAb) detection assay development for multi-domain drugs."
Poster Presenter: Gurleen Saini (Boehringer Ingelheim Pharmaceuticals, Inc., Danbury, Connecticut, United States)
Co-Authors: Karoline Eppler, Sophie Fessler, Theresa Locher, Hamid Samareh Afsari, Martin Laur, Lena Peter, Martin Herrmann, Matthias Kania, Rajeev Vesagopu, Mary Sanville
Boehringer Ingelheim Pharmaceuticals, Danbury, CT, USA
Day1-P18: "Overcoming IgE interference in PK and ADA assay of Omalizumab in the serum of asthma patients."
Poster Presenter: Nileshkumar Patel (Cliantha Research Ltd., Ahmedabad, Gujarat, Other/None, India)
Co-Authors: Dr. Shaifali Gupta
My HOD
Day1-P19: "Comparison of high-utility, multiplexed immunoassay platforms for streamlined clinical cytokine quantification"
Poster Presenter: Kevin McKinski (GSK, Collegeville, Pennsylvania, United States)
Co-Authors:
Day1-P20: "Development of a Robust Human Serum Cytokine A Assay as a Potential Biomarker to Support Clinical Studies"
Poster Presenter: Yun Liu (Teva Branded Pharmaceutical Products R&D, Inc., West Chester, Pennsylvania, United States)
Co-Authors: Peace Odey, Abigail Zhou, Thelma Angeles
Biomarker and Metabolism Analytics, Teva Branded Pharmaceutical Products R&D, Inc., West Chester, PA, USA
Day1-P21: "Leveraging Parallelism Assays to Validate the Accurate Detection of Endogenous Levels of Biomarkers in Ligand-Binding Assays
"
Poster Presenter: Shuangling Chen (Worldwide Clinical Trials , Austin, Texas, United States)
Co-Authors: Jessica Arroyo, Michaela Sousares, Brianda Lozoya
Worldwide Clinical Trials
Day1-P22: "Development and Validation of a Novel ECL Method for the Quantitation of Complement C3a/C3a desArg in Human Plasma."
Poster Presenter: Hong Luo (Eurofins BioPharma Analytical Services, St. Charles, Missouri, United States)
Co-Authors: 1) Brian Feldmann, MS; Elma Kesinger, BS; Ethan Grames, MS; Ruqi Wang, PhD and Erik Jerks, BS
2) Pallavi Gandhi, MS; Derek Wachtel, MS; Jeremy Beck
1) Eurofins BioPharma Analytical Services
2) Apellis Pharmaceuticals Inc.
Day1-P23: "Advancing Patient-Centric Neurological Biomarker Detection: Characterising Ultra-Sensitive Assays to Alleviate CSF Sampling Burden"
Poster Presenter: Morgan Evans (Agilex Biolabs, Adealide, Other/None, Australia)
Co-Authors: Coen Koch, Emily Zott, Kurt Sales
Agilex Biolabs
Day1-P24: "Novel DNA purification method facilitate the bioanalysis of DNA-based gene therapeutics in whole blood samples."
Poster Presenter: Maotian Zhou (WuXiappTec, Suzhou, Other/None, China)
Co-Authors: Maotian Zhou, Huan Yan, Miaomiao Song, Lili Xing, Yi Tao, Liang Shen
WuXi AppTec, Department of DMPK, 31 Yiwei Rd., Waigaoqiao Free Trade Zone, Shanghai, China
Posters on Main Workshop Day2 (Wednesday May 08, 2024, 2024)
Cell-Based, Flow Cytometry, PCR, NGS Assays and Gene/Cell Therapy and Vaccine Immunogenicity
Day2-P01: "Identification of Critical Reagent Leads using High-Throughput SPR"
Poster Presenter: James Fishburn (Pfizer, Bothell, Washington, United States)
Co-Authors: Arlan Martin, John Lindsay, Christine O'Day
Pfizer
Day2-P02: "Singlicate well assay for the analysis of Enoxaparin Pharmacodynamic Biomarkers (Anti-Factor Xa, Anti-Factor IIa, and TFPI) for the Bioequivalence study."
Poster Presenter: Ravi Shankar Maurya (Lambda Therapeutic Research Limited, Ahmedabad, Other/None, India)
Co-Authors: Mr. Bhavesh Prajapati, Ms. Komal Patel, Ms. Bhoomika Bhatt, Ms. Astha Yadav, Mr. Rishabh Patel, Mr. Hitendra Rana, Ms. Megha Barot, Mr. Ravi Maurya, Dr. Prashant Kale, Dr. M S Ramakrishnan.
Lambda Therapeutic Research Limited
Day2-P03: "Considerations for the use of ProteinSimple’s automated immunoassay platform Simple Plex™ in regulated bioanalysis"
Poster Presenter: Caroline Herndon (ICON Bioanalytical Laboratories, Whitesboro, New York, United States)
Co-Authors: Gabriella A. Cordo, James C. Chrisholm, Robert M. Kernstock, Mario J. Pellerin, Roger N. Hayes
ICON Laboratory Services, Whitesboro, NY, USA
Day2-P04: "Qualification of Opsonophagocytic killing Assays targeting Group B streptococcus using a novel beta-lactamase to inactivate beta-lactam antibiotics from umbilical cord and maternal serum."
Poster Presenter: Tina Biehl (MinervaX ApS, Frederiksberg, Other/None, Denmark)
Co-Authors: Tina Biehl, Majela Gonzalez-Miro, Feiruz Alamiri, Per B. Fischer & Bengt Johansson-Lindbom
MinervaX
Day2-P05: "Tissue Adenosine Distribution-Guided Gene Selection for the Development of a Composite Biomarker in Immuno-Oncology Therapy"
Poster Presenter: Corinne Ramos (Aliri, Loos, Other/None, France)
Co-Authors: Sandra Delebecq, Raphael Legouffe, Mathieu Gaudin, Shane Karnik
Aliri
Day2-P06: "Empowering T Cells in Vaccine Development: Optimized Assay Set-Ups for Lead Selection"
Poster Presenter: Annelies Turksma (Sanquin Diagnostic Services, Amsterdam, Other/None, Netherlands)
Co-Authors: Julian Freen-van Heeren 1, Rianne Opstelten 1, Sinead Lougheed 1, Annick de Vries 1, Anja ten Brinke 2
1 Immunomonitoring Services, R&D, Sanquin Diagnostic Services, Amsterdam, The Netherlands; Sanquin Diagnostic Services, Amsterdam, The Netherlands; 2 Sanquin Research, Amsterdam, The Netherlands
Day2-P07: "A Head-to-Head Comparison of Blood versus Buccal Swab in Pharmacogenomic Tests"
Poster Presenter: Tom Zhang (Worldwide Clinical Trials, Austin, Texas, United States)
Co-Authors: Jacob Blacutt
Thomas Lloyd
Worldwide Clinical Trials
Day2-P08: "Validation of an approach to measure high levels of neutralizing antibodies against AAV in human serum samples"
Poster Presenter: Travis Harrison (Precision for Medicine, Frederick, Maryland, United States)
Co-Authors: Travis Harrison*, Lisa Hoover*, Annette Feussner^, Jacqueline Tarrant^, Paul Hehir^, Tobi Guennel*, David Drubin*, Vivian Goodell*, Crystal Sung*, Deborah Phippard*
*Precision for Medicine; ^CSL Behring
Day2-P09: "Developing a cell-based AAV neutralization assay: no default scenario for specificity testing, PC selection, or threshold definition "
Poster Presenter: Florian Neff (Roche, Penzberg, Other/None, Germany)
Co-Authors: Michael Anthony, Kay-Gunnar Stubenrauch
Roche Innovation Center Munich (RICM), Roche Pharma Research and Early Development (pRED)
Day2-P10: "Comparison of the inhibitory dilution (ID50) method and a use of reference standard in assessing anti-viral titer in a COVID virus neutralization assay"
Poster Presenter: Atul Chaudhari (PPD, PART OF THERMO FISHER SCIENTIFIC, Richmond, Virginia, United States)
Co-Authors: Atul Chaudhari1, Hallie Bardsley1, Amber Maxwell1, Rebecca R. Greway2, Marie Bonhomme1, Tina Green2
1 Laboratory Services, Vaccine Sciences Lab, PPD®, Part of Thermo Fisher Scientific, Richmond, Virginia, United States of America, 2 Department of Laboratory Biostatistics, PPD®, Part of Thermo Fisher Scientific, Richmond, Virginia, United States of America
Day2-P11: "End-to-End Automation to Support Functional Cell-Based Assays and High Throughput Clinical Testing"
Poster Presenter: Eric Bauer (PPD, part of Thermo Fisher Scientific, Richmond, Virginia, United States)
Co-Authors: Brittany Fikes, Christopher John, Elizabeth Kowalski
PPD, part of Thermo Fisher Scientific, Richmond, Virginia, USA
Day2-P12: "Approaches to Method Qualification for Multiplex Ligand Binding Assay to Norovirus Virus-Like Particles "
Poster Presenter: Tin Bartholomew (Moderna, Inc., Norwood, Massachusetts, United States)
Co-Authors: Vick Amadu, Alexander O’ Roak, Liang Zhu, and Paul C Trampont
Clinical Biomarkers Laboratory, Moderna Inc., One Moderna Way, Norwood, MA 02062
Day2-P13: "High-quality RNA-seq Library Preparation from Formalin-Fixed Paraffin-Embedded (FFPE) tissues with GLP and GCLP Compliance "
Poster Presenter: Yixiao Cui (Frontage Laboratories, EXTON, Pennsylvania, United States)
Co-Authors: Yongzhong Zhao, Lili Liao, Jianqin He, Gillian Stinson, Robin Rodgers, Nan Zhang, John Lin
1760 Pennsylvania Drive, Exton, PA, 19341
Day2-P14: "Development and qualification of a non-clinical reverse transcription digital polymerase chain reaction (RT-dPCR) assay to quantify a mRNA therapeutic in plasma and tissue"
Poster Presenter: Muriel Smet (Sanofi, Zwijnaarde (Ghent), Other/None, Belgium)
Co-Authors: Joke Dumortier, Elien Van Nuffel, Katrien Lybaert, Melissa Lagrange, Sofie Poelmans, Marie-Paule Bouche and Samuel Pine
DMPK B&I, R&D, Sanofi, Ghent, Belgium
Day2-P15: "Comparison of assay performance between quantitative real-time PCR and a nanoplate-based digital PCR platform for use in bioanalysis of biodistribution studies"
Poster Presenter: Yanchun Li (Johnson&Johnson , Spring house, Pennsylvania, United States)
Co-Authors:
Day2-P16: "Comprehensive evaluation of multiple automated high throughput extraction platforms using Quantitative Real-Time PCR Assays "
Poster Presenter: Manisha Diaz (Eurofins Clinical Trial Solutions, Lenexa, Kansas, United States)
Co-Authors: Vikas Singh, Nicholas Lampe, Elijah Ybarra, Sharon Manley, Hikmat Al-Hashimi, Manisha Diaz, Mark Wissel
Eurofins Viracor BioPharma Services
Day2-P17: "Validation of a ddPCR Assay for the Human Lineage-Specific Multiple-Copy DUF1220 Domain to Quantify Human Cells in Cynomolgus Monkeys"
Poster Presenter: Akiko Suzuki (Shin Nippon Biomedical Laboratories, Ltd., Kagoshima, Other/None, Japan)
Co-Authors: Haruka Inoue, Naoki Kaname, Seulgi Lee, Yurie Okawa, Yukiko Arimura, Asako Uchiyama, and Tetsuya Yoshikawa
Shin Nippon Biomedical Laboratories, Ltd.
Day2-P18: "Assessment of Immunoglobulin class and subclass usage by single cell evaluation in an antigen-specific B cell Elispot assay after COVID-19 mRNA vaccination or natural SARS-CoV-2 infection"
Poster Presenter: Andrea Maul-Pavicic (Cellular Technology Limited, Shaker Heights, Ohio, United States)
Co-Authors: Lingling Yao, Noemi Becza, Zhigang Liu, Jack Chepke, Greg A. Kirchenbaum, Anton Gorbachev, Paul V. Lehmann
Cellular Technology Limited, 20521 Chagrin Boulevard, Shaker Heights, Ohio, USA
Day2-P19: "Implementation of automated gating and data analysis scripts to evaluate FACS-based pharmacodynamic effects in a Ph1 clinical trial. "
Poster Presenter: Michelle Graham (AbbVie, South San Francisco, California, United States)
Co-Authors: Michelle Graham, Diana Chen, Danqing Xu, Steve Keller
AbbVie, Inc. 1000 Gateway Blvd. South San Francisco, CA
Day2-P20: "Development and Validation of a High-Dimensional Regulatory T-cells Spectral Flow Cytometry Assay"
Poster Presenter: Calin Marian (Merck, Rahway, New Jersey, United States)
Co-Authors: Kamakshi Balakrishnan, Megan McCausland, Todd Rogers and Luis A. Mendez
Translational Molecular Biomarkers, Flow Cytometry, Merck & Co., Inc., Rahway, NJ, USA & Q2 Solutions, Marietta, GA, USA
Day2-P21: "Critical Reagent Characterization of Biotinylated Antibody Conjugates in a Flow Cytometry-Based Receptor Occupancy Assay"
Poster Presenter: Megan Rasmussen (Celerion Inc., Lincoln, Nebraska, United States)
Co-Authors: Rasmussen, Megan L., Urlacher, Teresa M., and Stanta, Johannes L.
Molecular and Cell Biology, Bioanalytical Services, Celerion Inc.
Day2-P22: "Performance Qualification of BD FACS Symphony A5 Spectrally Enabled Instruments using Fluorescent Beads with National Institute of Standards and Technology (NIST) Assigned equivalent reference fluorophore (ERF) Values"
Poster Presenter: Ruqi Wang (Eurofins, Saint Charles, Missouri, United States)
Co-Authors: Susmita Jasti2 , Jordyn Westergaard2, Courtney Stoker2, Thomas Beadnell2, Virginia Litwin3
2Eurofins Viracor BioPharma, Lenexa, Kansas, USA
3Eurofins BioPharma Services, Montréal, Québec, Canada
Day2-P23: "Advancing the Frontiers: Development and Qualification of High Dimensional Spectral Flow Cytometry Intracellular and Surface Immunophenotyping Assays for Human Clinical Trials"
Poster Presenter: Kevin Lang (PPD, part of Thermo Fisher Scientific, Richmond, Virginia, United States)
Co-Authors: Adam Rupert, Spencer Hebert, Emily Bauer, Lauren Fryzlewicz, Vellalore Kakkaniah
PPD, part of Thermo Fisher Scientific
Day2-P24: "Development of Safe Immunogenicity Assays for Pathogenic Influenza Strains"
Poster Presenter: Kyle Doolan (Integral Molecular, Philadelphia, Pennsylvania, United States)
Co-Authors: Kyle Doolan (presenting author), Lewis J. Stafford, Chidananda Sulli, Allison Sheetz, Parul Ganjoo, Vlada Kupriienko, Maya Cabot, Nathan Krump, Benjamin Doranz
Integral Molecular
Day2-P25: "A novel whole blood cryopreservation method for flow cytometry based leucocyte immunophenotyping"
Poster Presenter: Xiaochen Guo (WuXi AppTec (Suzhou) Co., Ltd., suzhou, Other/None, China)
Co-Authors: QinLei Gu, Mingdong Fu, Chengyu Li, Ziqiang Hou, Rongrong Zhai, Xuemei Zhang, Bo Wei, Jinpeng Li, Xiaoying Jin
WuXi AppTec (Suzhou) Co., Ltd.
Posters on Main Workshop Day3 (Thursday May 09, 2024, 2024)
Mass Spectrometry Assays and Tissues Analysis by LBA and Critical Reagents
Day3-P01: "Leveraging a Platform Approach for Lipid Nano Particle (LNP) Analysis in Pharmacokinetics, Toxicokinetic, and Biodistribution Studies of mRNA Therapeutics"
Poster Presenter: Harkewal Singh (Moderna, Cambridge, Massachusetts, United States)
Co-Authors: Kelin Wang
Moderna
Day3-P02: "Validation of quantitation of MK-6598 target protein and phenylpyruvate in tumor biopsies by LCMSMS to inform target engagement in Phase I oncology clinical trial. "
Poster Presenter: Carolina Cabral (Merck, Rahway, New Jersey, United States)
Co-Authors: Carolina Cabral, Stuart Shumway, Erik Henry Knelson, Omobolaji O Akala and Michael Lassman
Merck Sharp & Dohme LLC
Day3-P03: "Identification of Surrogate Peptides of Rabbit IgG, IgM and IgA for Anti-Drug Antibody (ADA) Isotyping and Evaluation of Direct and Indirect Immunoprecipitation Strategies Towards ADA Semi-Quantitation by Hybrid LC/MS/MS"
Poster Presenter: Yu Hui (PPD, Part of Thermo Fisher Scientific, Richmond, Virginia, United States)
Co-Authors: Yu Hui1, Moucun Yuan1, Kumar Shah1, William R. Mylott1, M. Shane Woolf1, Joe Palandra2 and Mike Baratta2
1Analytical Services Division (ASD), PPD, Part of Thermo Fisher Scientific, Richmond, VA
2Takeda Development Center Americas, Inc., Cambridge, MA
Day3-P04: "Evaluation of Patient Centric Sampling using Tasso Capillary Blood Microsampling Devices in Comparison to Conventional Venous Plasma Blood Sampling for Pharmacokinetic Assessment of Zavegepant"
Poster Presenter: Ogert Fisniku (Pfizer, Mount Prospect, Illinois, United States)
Co-Authors: Ogert Fisniku, Katty Wan, Amanda Mattson, Daria Wentzel, Jing Liu, Mohamed Shahin, Olga Kavetska
Ogert Fisniku, Katty Wan, Jing Liu, Mohamed H. Shahin, and Olga Kavetska are Pfizer employees. Amanda Mattson and Daria Wentzel are Syneos Health.
Day3-P05: "Bioanalytical considerations for LC-MS/MS method development of excipient quantification in plasma using a case study with BRIJ® L23"
Poster Presenter: Ariane Kahnt (Johnson & Johnson Innovative Medicine, Beerse, Other/None, Belgium)
Co-Authors: Luc Diels, Emmanuel Njumbe Ediage, Lieve Dillen, Tom Verhaeghe
Johnson & Johnson Innovative Medicine
Day3-P06: "Overcoming obstacles: strategies and challenges in developing a validated quantitation assay for a novel therapeutic peptide"
Poster Presenter: Thomas Tang (Genentech, South San Francisco, California, United States)
Co-Authors: Liuxi Chen, Xiaorong Liang, Brian Dean
Genentech
Day3-P07: "Quantification of IRAK4 by immunocapture LC-MS/MS in human whole blood"
Poster Presenter: Johanna Paris (Sanofi, Montpellier, Other/None, France)
Co-Authors: Johanna Paris, Catherine Aubert & Sandrine Descloux
Sanofi Montpellier
Day3-P08: "Bicycle Toxin Conjugate (BTC) quantitative bioanalysis: A comprehensive bioanalytical assay for the quantitation of BT8009 and MMAE supporting GLP toxicokinetic evaluations"
Poster Presenter: Ying Zhang (Bicycle Therapeutics, Cambridge, Massachusetts, United States)
Co-Authors: Joseph A Tweed1, Ying Zhang1, Fern Adams-Dam2, Jane Allanson2, Kevin Holmes2, Alex Leonard2, Justin Bader1, Hongmei Xu1, Mike Rigby3 and Phil Jeffrey3
1Bicycle Therapeutics, Cambridge, MA 02140, USA
2York Bioanalytical Solutions Limited, York, YO26 6QR, UK
3Bicycle Therapeutics, Cambridge, CB21 6GS, UK
Day3-P09: "Development of a sensitive LC-MS/MS assay to support human microdose study for an oral agonist of the GLP-1 receptor"
Poster Presenter: Eugene Kadar (Pfizer, Groton, Connecticut, United States)
Co-Authors: Eugene P. Kadar, Heather Eng, Amit S. Kalgutkar, Christopher L. Holliman, and Gregory S. Steeno1
Pfizer
Day3-P10: "The importance of sample clean up demonstrated by the revalidation of the biomarker 4β-hydroxycholesterol for assay robustness"
Poster Presenter: Troy Voelker (Aliri Bioanalysis, Salt Lake City, Utah, United States)
Co-Authors: Qian Guo, Ph.D., Brandon Wilcock Ph.D., Ryan Adler, M.S., Scott Reuschel, M.S., Juan Rogness, M.S., Nick Banks, B.S.
Aliri Bioanalysis
Day3-P11: "Time Course Analysis of Drug-Antibody Ratio of Disitamab vedotin in Rat Plasma"
Poster Presenter: Shiori Miyawaki (Shin Nippon Biomedical Laboratories, Ltd., Kainan, Wakayama, Other/None, Japan)
Co-Authors: Suguru Fukuda, Koichiro Hori, Yuki Nishimura, Taiki Aikawa, Fumi Tanaka, Kazunari Hirowatari, Katsunori Ieki
Shin Nippon Biomedical Laboratories, Ltd.
Day3-P12: "A Plate-based, Automated Liquid/Liquid Extraction (LLE) Method for Improved Operational Efficiency of LC-MS/MS Methods "
Poster Presenter: Leimin Fan (Worldwide Clinical Trials - Austin, TX, Austin, Texas, United States)
Co-Authors: Alicia Bian, JP Kotha
Worldwide Clinical Trials
Day3-P13: "Automating Selection for Incurred Sample Reanalysis: A Meta-Analytical-Based Algorithm for Error Reduction"
Poster Presenter: Jack Rogers (KCAS Bio, Olathe, Kansas, United States)
Co-Authors: Jessie Allen, Yoka Thomas, Cheikh Kane
KCAS Bio
Day3-P14: "Introducing immunocapture to simultaneously improve selectivity, sensitivity, efficiency, and analysis time in LCMSMS measurement of Vitamin D2"
Poster Presenter: Jérôme Bergeron (Syneos Health, Quebec, Quebec, Canada)
Co-Authors: Nadine Lafontaine, Valérie Montminy, Marie-Eve Doyon, Sylvain Lachance, Jérôme Bergeron
Syneos Health, Quebec City, QC, Canada
Day3-P15: "Development, validation and cross-validation of a bioanalytical method for analysis of drug levels in blood samples collected using a microsampling device"
Poster Presenter: Nancy Lampron (Syneos Health, Quebec, Quebec, Canada)
Co-Authors: Louis-Charles Boisvert, Marie-Eve Doyon, Nancy Lampron, Sylvain Lachance and Jérôme Bergeron
Syneos Health, Quebec City, QC, Canada
Day3-P16: "Validation of a Hybrid IP/LC/MS/MS Assay with EVOSEP cleanup for the quantitation of Islet Amyloid polypeptide in human plasma"
Poster Presenter: Shane Karnik (Aliri Bioanalysis, COLORADO SPGS, Colorado, United States)
Co-Authors: Gianni García-Faroldi
Susanna Nybond
Sara Rapp
Carissa Jones
Matthew Hartle
Edward Brewer
Mercodia
Aliri Bioanalysis
Day3-P17: "Tiny Tubes, Big Impact: Advancing 3R Principles by Developing Capillary Microsampling LC–MS/MS for the Quantification of CRN04894 in Rat Plasma."
Poster Presenter: Mitesh Sanghvi (Pharmaron, Germantown, Maryland, United States)
Co-Authors: Mitesh Sanghvi1, Junlong Shao1, Angel Madariaga1, Stephanie Dunchock2, Jian Wang2 and Barry Jones2
1Pharmaron, Germantown, Maryland;
2Crinetics Pharmaceuticals, San Diego, California
Day3-P18: "Development of an immunocapture LC/MS assay for transgene expression quantification using commercially available anti-protein antibody to support multi-species gene therapy program"
Poster Presenter: Ben Nie (BioAgilytix Labs, San Diego, California, United States)
Co-Authors: Ben Nie, Christian Smith, Andrew Bergdorf, Dave Beyerlein
BioAgilytix Labs
9050 Camino Santa Fe, San Diego, CA 92121
Day3-P19: "Developmental Factors that may affect a Hybridization ELISA Assay to quantitate an Anti-Sense Oligonucleotide of an siRNA in Human Serum"
Poster Presenter: Wendy Cheung (Pharmaron (Germantown) Lab Services, Germantown, Maryland, United States)
Co-Authors: Wendy Cheung, Nigus Ambaye
Pharmaron, Germantown, Maryland
Day3-P20: "A High-Throughput and Cost-Efficient Assay for Quantification of a Novel Monoclonal Antibody Anselamimab in Human Serum using Streamlined Sample Extraction Coupled with LC-MS/MS"
Poster Presenter: Yuehui Ma (Resolian (Formally Alliance Pharma), Malvern, Pennsylvania, United States)
Co-Authors: Mary (Yuehui) Ma1, Darcy Merrill1, and Aihua Liu1
Mark Dysinger2, Ming Li2
1: Resolian, Malvern, PA 19355
2: Alexion, Astra Zeneca Rare Disease, New Haven, CT 06510
Day3-P21: "Quantitative LC-MS Analysis of Two siRNAs in Rat Tissues and Plasma: Innovative Sample Extraction Strategies for Enhanced Robustness"
Poster Presenter: David Zuluaga-Rave (Alliance Pharma, Malvern, Pennsylvania, United States)
Co-Authors: David Zuluaga1, Nuozhou (Noah) Chen1, Lief Morin1, Zhe Xu1, Aihua Liu1
Yunlin Fu2, Wenkui Li2
1Resolian, Inc., Malvern, PA, USA,
2 Novartis Pharmaceuticals, East Hanover, NJ, USA.
Day3-P22: "Improved Identification and Estimated Quantitation of Oligonucleotide Metabolites by HPLC-HRAMS"
Poster Presenter: Kathleen McQuate (Charles River Laboratories, Ashland, Ohio, United States)
Co-Authors: Dino Petrov, Noah Post, Kathleen McQuate, Seth Bell
Charles River Laboratories-Ashland, Ashland, OH, Ionis Pharmaceuticals, Carlsbad, CA
Day3-P23: "Development and validation of a fit for purpose biomarker LC-MS/MS assay measuring 15 plasma bile acids"
Poster Presenter: Aaron Ledvina (Labcorp, Inc, Madison, Wisconsin, United States)
Co-Authors: David Humphries, Nicholas Saichek, Owen Walcott, Circe McDonald, Wildaliz Nieves, Matt Peach, Ann Qin
David Humphries, Nicholas Saichek, Owen Walcott would be affiliated with Labcorp as well.
Circe McDonald, Wildaliz Nieves, Matt Peach, Ann Qin are with Gilead Sciences Inc.
Day3-P24: "M-Protein Measurement in Plasma of Multiple Myeloma Patients by Intact Mass Spectrometry: A Promising Orthogonal Approach to MRD Measurement by NGS and Next Gen Flow Cytometry."
Poster Presenter: Luca Genovesi (CellCarta, Montreal, Quebec, Canada)
Co-Authors: Luca Genovesi, Michael Schirm, Nick Dupuis, Gwenael Pottiez
CellCarta
Day3-P25: "LCMS based strategies for in vivo DAR characterization in NHP Serum"
Poster Presenter: Jing Huang (WuXi AppTec (Suzhou) Co., Ltd., Suzhou, Other/None, China)
Co-Authors: Jing Huang1, Yifan Wang1, Pei Zhang1, Wenqin Xu1, Tongtong Chen1, Ming Liu1, Ke Li1, Xiaoying Jin1, Lan Li2
1WuXi AppTec, 1318 WuZhong Avenue, Suzhou, Jiangsu, China.
2WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, China.
For Poster Presenters:
- Mandatory Presenting Time:
- During both Morning Break and Afternoon Break of the Day of your Poster - at your poster to answer questions
- Mount Time:
- Tue-Thu: 7am to 7:30am
- Take-down Time:
- Tue-Wed: 5:30pm to 6:30pm
- Thu: 4:20pm right after the Afternoon Break
Note: Removing your poster before the take-down time is NOT permitted
Poster Award:
There is poster contest at WRIB each year. Presenters of 3 most outstanding posters will each recieve free registration for next WRIB Main Workshop, as well as an interview by Bioanalysis Journal team, and appearing in a speical feature report in the Bioanalysis Journal and on Bioanalysis Zone.
Poster Board Size:
The size of our poster boards is 8'X4' (8 feet wide and 4 feet high) - standard size as the ones used at most other conferences
