Specialized Workshop T1 - Tuesday April 08, 2025: 7am to 5:45pm - Discussion Topic List

" Mass Spectrometry Assays - Latest Advances, Challenges and Solutions from Internationally Recognized Key Opinion Leaders"

Understanding the Challenges of Mass Spec Applications to Novel Modalities; Advanced/Innovative Applications of Automation/Robotic, Machine Learning in Mass Spec; Strategies & Novel Case Studies for Complex Method Development for Next-Generation of Small Molecules, Peptides, Oligonucleotides (mRNA, siRNA, LNP, Nanoliposomes), Protein Degraders and Macrocylic/Large Molecules/ADC; Lesson Learned from Mass Spec Innovative Approaches and Technology Advancements in Multiplexing Discovery Bioanalysis; Influence of Different Sample Preparation Approaches in Tissues; Bioanalysis by MS/MS Activation, and Spectral Annotation in HRMS using the Latest Generation of QTOF/Orbitrap; Mass Spec of Protein Drugs, Biomarkers and Transgene; Increasing Bioanalytical Selectivity & Sensitivity in Presence of Isobaric Interferences; Application of Discovery Bioanalysis Solution to Regulated Bioanalysis; AND LASTLY, WRIB Traditional KOL Industry Focused and Highly Interactive Panel Discussions on Discovery/Regulated Mass Spectrometry Applications and Recent Controversial Issues

Session 1: Biomarker Assays Advanced Strategies for Method Development/FFP BAV: FFPE Tissue, GIP Panel and Low Abundant Proteins

Session 2: Hybrid Assays (IA-MS) for PK: Advanced Strategies for ADC, Glycoproteins, Biotransformation and ICH M10 FFP Validation

Session 3: New Small Molecules Challenges and Ultra Sensitivity Mass Spec in Discovery & Regulated Bioanalysis

Session 4: High Quality/Throughput Tissue Measurements to support Oligonucleotides and Biomarkers

Session 5: 2024 White Paper in Bioanalysis

  • 2024 White Paper on Mass Spectrometry Assays - Latest Advances, Challenges and Solutions from Internationally Recognized Key Opinion Leaders

    Consensus & Conclusions on Mass Spectrometry Assays - Latest Advances, Challenges and Solutions from Internationally Recognized Key Opinion Leaders for 2024 White Paper





Agenda at a Glance Agenda at a Glance