"Mass Spectrometry Assays - Latest Advances, Challenges and Solutions from Internationally Recognized Key Opinion Leaders"
Cutting-edge Mass Spec (MSA) methodologies in drug discovery/development applied to Novel Modalities, Protein Drugs, Biomarkers and Transgene; Automation/Robotic in Mass Spec; Innovative applications of Mass Spec in AAV Gene Therapy; Novel IA-MS developments for Bispecific T Cell Engager; Strategies & novel case studies for complex method development for next-generation of Small Molecules Covalent Inhibitors, Peptides, Oligonucleotides (mRNA, siRNA, LNP, nanoliposomes), Antibody Oligonucleotide Conjugates (AOC), Targeted Protein Degraders and Macrocylic/Large Molecules; Lesson Learned from Mass Spec Innovative Approaches and Technology Advancements for Dual-Payload ADCs by Integrated Bioanalytical Strategies to overcome instability issues; Strategies for improving throughput, sensitivity, resolution and multiplexed capabilities for Liposomal & Covalent drugs, Prodrugs and Low-abundance Peptides; Challenges in Quantitation of Encapsulated Nanoparticle Payloads; Developments in HRMS Increasing bioanalytical selectivity & sensitivity in presence of Isobaric Interferences; Measurement of biotherapeutics in in Formalin Fixed Paraffin Embedded Tumor; Application of Discovery Bioanalysis solution to Regulated Bioanalysis. Traditional KOL Industry/Regulators focused and highly interactive panel discussions on Discovery/Regulated Mass Spectrometry applications and recent Controversial Issues.
Session 1: Enhanced MS Approaches for Glycoforms Quantification/Changes & Deglycosidation
Session 2: Latest Strategy to ensure Consistent Biomarker Measurement: Parallelism, Nano-Flow, Derivatization
Session 3: Emerging ADC Formats: Bispecific/Dual Payload ADC and Addressing Cleavable vs Non-cleavable Linkers
Session 4: The Power of Simplicity: MSA shaping the Future of Bioanalysis for Oligos, Peptides, and Complex Therapeutics
Session 5: 2027 White Paper in Bioanalysis
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2027 White Paper on Mass Spectrometry Assays
Consensus & Conclusions on Mass Spectrometry Assays for 2027 White Paper
