Specialized Workshop T1 - Tuesday April 14, 2026: 7am to 5:30pm
"AGENDA - Mass Spectrometry Assays - Latest Advances, Challenges and Solutions from Internationally Recognized Key Opinion Leaders"
| 07:00am-08:00am: | Start your day at WRIB with Networking Continental Breakfast in the Exhibit Room |
Session 1: Enhanced MS Approaches for Glycoforms Quantification/Changes & Deglycosidation
Chair: Ms. Sharin Roth, Senior Director Bioanalysis, Translational Research & Biomarkers, Otsuka| 08:00am-08:20am: |
Ms. Sandrine Descloux, Head of Hybrid Bioanalytical platform, Sanofi "How did LC-MS succeed to derisk a mAb clinical program ?" |
| 08:20am-08:40am: |
Dr. Jian Chen, Associate Director Bioanalysis, Bristol Myers Squibb "Assessing in vivo DAR values using HRMS with case studies to support nonclinical and clinical ADC development" |
| 08:40am-09:00am: |
Dr. Linzhi Chen, Bioanalytical Group Leader & Senior Research Fellow, Boehringer Ingelheim Dr. Wei Wei, SME HRMS & Principal Scientist DMPK, Boehringer Ingelheim "Immunocapture-LC/HRMS Intact Analysis for Investigating PNU-ADC Deglycosidation in Vivo" |
| 09:00am-09:20am: |
Ms. Sandrine Descloux, Head of Hybrid Bioanalytical platform, Sanofi
Dr. Jian Chen, Associate Director Bioanalysis, Bristol Myers Squibb Dr. Linzhi Chen, Bioanalytical Group Leader & Senior Research Fellow, Boehringer Ingelheim Dr. Wei Wei, SME HRMS & Principal Scientist DMPK, Boehringer Ingelheim "Panel Discussions on Enhanced MS Approaches for Glycoforms Quantification/Changes & Deglycosidation " |
| 09:20am-10:10am: | Networking Coffee Break with Morning Snacks in the Exhibit Room |
Session 2: Latest Strategy to ensure Consistent Biomarker Measurement: Parallelism, Nano-Flow, Derivatization
Chair: Dr. John Williams, Senior Director DMPK Bioanalysis, Vertex| 10:10am-10:30am: |
Dr. Barry Jones, Director Bioanalysis & Biomarker , Crinetics "Parallelism of small molecule biomarkers by MSA revisited; the value of dilution-based parallelism" |
| 10:30am-10:50am: |
Mr. Alex Behling, Assistant Director, Bioanalytical Lead, Clinical Biomarkers, Ionis "Nano-Flow LCMS Fit-For-Purpose Validations for Rare Disease Biomarkers: Case Studies and Lessons Learned" |
| 10:50am-11:10am: |
Dr. Linna Wang, Associate Director Bioanalysis & Biomarker , Crinetics "Scientific-Driven Preclinical Biomarker Strategy: Novel Case Studies and Lesson Learned" |
| 11:10am-11:30am: |
Dr. Michael Hoover, Associate Director Integrated Bioanalysis , AstraZeneca "Navigating bioanalytical challenges in LC-MS based biomarker development" |
| 11:30am-11:50am: |
Dr. Barry Jones, Director Bioanalysis & Biomarker , Crinetics
Mr. Alex Behling, Assistant Director, Bioanalytical Lead, Clinical Biomarkers, Ionis Dr. Linna Wang, Associate Director Bioanalysis & Biomarker , Crinetics Dr. Michael Hoover, Associate Director Integrated Bioanalysis , AstraZeneca "Panel Discussions on Latest Strategy to ensure Consistent Biomarker Measurement: Parallelism, Nano-Flow, Derivatization " |
Session 3: Emerging ADC Formats: Bispecific/Dual Payload ADC and Addressing Cleavable vs Non-cleavable Linkers
Chair: Dr. Weili Yan, Bioanalytical Assay Manager , Genentech| 11:50am-12:10pm: |
Dr. Ang Liu, Director Bioanalysis, Development PK, J&J "Navigating the Evolving ADC Landscape - From Bioanalytical Strategies to Operational Considerations" |
| 12:10pm-01:10pm: |
Sit-down Hot Buffet Networking Lunch downstairs at Marsalis B Note: Lunch Desserts and Coffee/Tea are served in the Exhibit Room |
| 01:10pm-01:30pm: |
Dr. Guifen Xu, Senior Director Preclinical Development, Sutro Biopharma "Bioanalysis of Dual-Payload ADCs by LC-MS/MS: Strategy & Challenges" |
| 01:30pm-01:50pm: |
Dr. Hermes Licea-Perez, Director, Technology Leader Biomarker & Bioanalytical Platforms, GlaxoSmithKline "Identification and Quantitation of Thiol-Conjugated Linker-Payload Metabolites in ADCs with Cleavable Linkers" |
| 01:50pm-02:10pm: |
Dr. Ang Liu, Director Bioanalysis, Development PK, J&J
Dr. Guifen Xu, Senior Director Preclinical Development, Sutro Biopharma Dr. Hermes Licea-Perez, Director, Technology Leader Biomarker & Bioanalytical Platforms, GlaxoSmithKline "Panel Discussions on Emerging ADC Formats: Bispecific/Dual Payload ADC and Addressing Cleavable vs Non-cleavable Linkers " |
Session 4: The Power of Simplicity: MSA shaping the Future of Bioanalysis for Oligos, Peptides, and Complex Therapeutics
Chair: Dr. Xiaobin Xu, Associate Director Analytical & Biological Mass Spectrometry, Regeneron| 02:10pm-02:30pm: |
Dr. Guodong Zhang, Director, Group Head Bioanalytical & DMPK, Alnylam "hLCMS PK assays in plasma and tissues" |
| 02:30pm-02:50pm: |
Dr. Estelle Maes, Director Quantitative, Translational & ADME Sciences, AbbVie "Therapeutic Peptides LC-MS Bioanalysis and ADME: Approaches and Case Studies" |
| 02:50pm-03:10pm: |
Mr. Kevork Mekhssian, Senior Director Bioanalytical Sciences, Altasciences "Advances in LC-MS workflows for complex therapeutics and biomarkers" |
| 03:10pm-04:10pm: |
Networking Break with Afternoon Snacks, and Wine and Beer Reception in the Exhibit Room |
| 04:10pm-04:30pm: |
Dr. Guodong Zhang, Director, Group Head Bioanalytical & DMPK, Alnylam
Dr. Estelle Maes, Director Quantitative, Translational & ADME Sciences, AbbVie Mr. Kevork Mekhssian, Senior Director Bioanalytical Sciences, Altasciences "Panel Discussions on The Power of Simplicity: MSA shaping the Future of Bioanalysis for Oligos, Peptides, and Complex Therapeutics" |
Session 5: 2026 White Paper in Bioanalysis
| 04:30pm-05:30pm: |
Ms. Sharin Roth, Senior Director Bioanalysis, Translational Research & Biomarkers, Otsuka Dr. John Williams, Senior Director DMPK Bioanalysis, Vertex Dr. Weili Yan, Bioanalytical Assay Manager , Genentech Dr. Xiaobin Xu, Associate Director Analytical & Biological Mass Spectrometry, Regeneron "Recommendations on Mass Spectrometry Assays and Panel Discussions for 2026 White Paper in Bioanalysis" |
